RLTPR anticorps (AA 1136-1290)

N° du produit ABIN7146660

Détail du produit anti-RLTPR anticorps

Antigène: RLTPR (RGD Motif, Leucine Rich Repeats, Tropomodulin Domain and Proline-Rich Containing (RLTPR))

Épitope: AA 1136-1290

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RLTPR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Capping protein, Arp2/3 and myosin-I linker protein 2 protein (1136-1290AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RLTPR

Antigène: RLTPR (RGD Motif, Leucine Rich Repeats, Tropomodulin Domain and Proline-Rich Containing (RLTPR))

Autre désignation: CARMIL2 (RLTPR Produits)

Synonymes: anticorps CG1399-PB, anticorps D130029J02Rik, anticorps Gm585, anticorps CARMIL2, anticorps CARMIL2b, anticorps LRRC16C, anticorps capping protein regulator and myosin 1 linker 2, anticorps F-actin-uncapping protein RLTPR, anticorps RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing, anticorps Carmil2, anticorps CARMIL2, anticorps LOC100021093, anticorps LOC100091608, anticorps RLTPR

Sujet:

Background: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization (PubMed:26466680). Plays a role in cell protrusion formations, involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations (PubMed:19846667, PubMed:26578515, PubMed:26466680). Involved as well in cell migration and invadopodia formation during wound healing (PubMed:19846667, PubMed:26578515, PubMed:26466680).

Aliases: CARMIL2 antibody, CARMIL2b antibody, Leucine rich repeat containing 16C antibody, leucine-rich repeat antibody, Leucine-rich repeat-containing protein 16C antibody, LR16C_HUMAN antibody, LRRC16C antibody, RGD antibody, RGD leucine rich repeat tropomodulin and proline rich containing protein antibody, RGD motif leucine rich repeats tropomodulin domain and proline rich containing antibody, Rltpr antibody, tropomodulin and proline-rich-containing protein antibody

UniProt: Q6F5E8