DNAJC3 anticorps (AA 277-496)

N° du produit ABIN7150550

Détail du produit anti-DNAJC3 anticorps

Antigène: DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))

Épitope: AA 277-496

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJC3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DnaJ homolog subfamily C member 3 protein (277-496AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DNAJC3

Antigène: DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))

Autre désignation: DNAJC3 (DNAJC3 Produits)

Synonymes: anticorps ERdj6, anticorps HP58, anticorps P58, anticorps P58IPK, anticorps PRKRI, anticorps zgc:56356, anticorps zgc:77731, anticorps wu:fb64f06, anticorps DNAJC3, anticorps dnajc3, anticorps DDBDRAFT_0186884, anticorps DDBDRAFT_0233602, anticorps DDB_0186884, anticorps DDB_0233602, anticorps cg8286, anticorps AA408985, anticorps AU067833, anticorps Dnajc3a, anticorps Dnajc3b, anticorps Prkri, anticorps mp58, anticorps p58, anticorps p58IPK, anticorps fc17a06, anticorps prkri, anticorps wu:fc17a06, anticorps DnaJ heat shock protein family (Hsp40) member C3, anticorps DnaJ (Hsp40) homolog, subfamily C, member 3a, anticorps DNAJ heat shock N-terminal domain-containing protein, anticorps DnaJ heat shock protein family (Hsp40) member C3 L homeolog, anticorps DnaJ (Hsp40) homolog, subfamily C, member 3b, anticorps DNAJC3, anticorps dnajc3a, anticorps dnajc3, anticorps dnajc3.L, anticorps Dnajc3, anticorps dnajc3b

Sujet:

Background: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at \\\'Ser-52\\\' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.

Aliases: DnaJ (Hsp40) homolog subfamily C member 3 antibody, DnaJ homolog subfamily C member 3 antibody, DNAJC3 antibody, DNJC3_HUMAN antibody, double-stranded RNA-activated protein kinase inhibitor antibody, Endoplasmic reticulum DnaJ protein 6 antibody, ERdj6 antibody, HP58 antibody, Interferon induced, double stranded RNA activated protein kinase inhibitor antibody, Interferon-induced antibody, P58 antibody, p58 ipk antibody, P58IPK antibody, PRKRI antibody, Protein kinase inhibitor of 58 kDa antibody, Protein kinase inhibitor p58 antibody, Protein kinase interferon inducible double stranded RNA dependent inhibitor antibody

UniProt: Q13217

Pathways: ER-Nucleus Signaling