PTPRB anticorps (AA 1758-1997)

N° du produit ABIN7167501

Détail du produit anti-PTPRB anticorps

Antigène: PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))

Épitope: AA 1758-1997

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRB est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Receptor-type tyrosine-protein phosphatase beta protein (1758-1997AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PTPRB

Antigène: PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))

Autre désignation: PTPRB (PTPRB Produits)

Synonymes: anticorps PTPRB, anticorps HPTP-BETA, anticorps HPTPB, anticorps PTPB, anticorps R-PTP-BETA, anticorps VEPTP, anticorps 3230402H02Rik, anticorps C130094E24, anticorps Ptpz, anticorps Rptpb, anticorps VE-PTP, anticorps Veptp, anticorps protein tyrosine phosphatase, receptor type B, anticorps receptor-type tyrosine-protein phosphatase beta, anticorps protein tyrosine phosphatase, receptor type, B, anticorps PTPRB, anticorps LOC100380677, anticorps Ptprb

Sujet:

Background: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity).

Aliases: HPTP BETA antibody, HPTPB antibody, Phosphacan receptor type B antibody, Protein tyrosine phosphatase receptor type B antibody, Protein-tyrosine phosphatase beta antibody, PTPB antibody, Ptprb antibody, PTPRB_HUMAN antibody, R PTP BETA antibody, R-PTP-beta antibody, Receptor-type tyrosine-protein phosphatase beta antibody, RPTPB antibody, Vascular endothelial protein tyrosine phosphatase antibody, VE-PTP antibody

UniProt: P23467