DROSHA anticorps (AA 1-100) (HRP)

N° du produit ABIN7168102

Détail du produit anti-DROSHA anticorps (HRP)

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DROSHA est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogène: Recombinant Human Ribonuclease 3 protein (1-100AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DROSHA

Antigène: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Autre désignation: DROSHA (DROSHA Produits)

Synonymes: anticorps im:7150667, anticorps zgc:158612, anticorps ETOHI2, anticorps HSA242976, anticorps RANSE3L, anticorps RN3, anticorps RNASE3L, anticorps RNASEN, anticorps 1110013A17Rik, anticorps AI874853, anticorps Etohi2, anticorps Rn3, anticorps Rnasen, anticorps RGD1307626, anticorps ribonuclease type III, nuclear, anticorps Ribonuclease 3, anticorps ribonuclease 3, anticorps drosha ribonuclease III, anticorps drosha, ribonuclease type III, anticorps rnasen, anticorps Thicy_0885, anticorps Sinme_0866, anticorps Isova_2087, anticorps Sphch_0770, anticorps DROSHA, anticorps Drosha

Sujet:

Background: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3\' and 5\' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.

Aliases: DROSHA antibody, Drosha double stranded RNA specific endoribonuclease antibody, Drosha ribonuclease type III antibody, Etohi2 antibody, HSA242976 antibody, Nuclear RNase III Drosha antibody, p241 antibody, Protein Drosha antibody, Putative protein p241 which interacts with transcription factor Sp1 antibody, Putative ribonuclease III antibody, RANSE3L antibody, Ribonuclease 3 antibody, Ribonuclease III antibody, Ribonuclease III nuclear antibody, Ribonuclease type III nuclear antibody, RibonucleaseIII antibody, RN 3 antibody, RN3 antibody, RNase 3 antibody, RNase III antibody, RNase3 antibody, RNASE3L antibody, RNaseIII antibody, RNASEN antibody, RNC_HUMAN antibody

UniProt: Q9NRR4

Pathways: Regulatory RNA Pathways