UBA52 anticorps (AA 1-128) (FITC)

N° du produit ABIN7174411

Détail du produit anti-UBA52 anticorps (FITC)

Antigène: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Épitope: AA 1-128

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBA52 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ubiquitin-60S ribosomal protein L40 protein (1-128AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur UBA52

Antigène: UBA52 (Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 (UBA52))

Autre désignation: UBA52 (UBA52 Produits)

Synonymes: anticorps CEP52, anticorps HUBCEP52, anticorps L40, anticorps RPL40, anticorps D8Ertd21e, anticorps Gm1863, anticorps Rps27a, anticorps Ubb, anticorps Ubc, anticorps UBCEP2, anticorps UB-RPL40, anticorps MGC80109, anticorps cep52, anticorps hubcep52, anticorps rpl40, anticorps RPS27A, anticorps UBB, anticorps UBC, anticorps wu:fa91f08, anticorps zgc:123344, anticorps UBA52, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1, anticorps ubiquitin A-52 residue ribosomal protein fusion product 1 L homeolog, anticorps UBA52, anticorps Uba52, anticorps uba52.L, anticorps uba52

Sujet:

Background: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

Aliases: UBA52 antibody, UBCEP2 antibody, Ubiquitin-60S ribosomal protein L40 antibody, CEP52 antibody, Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin, 60S ribosomal protein L40 antibody, Large ribosomal subunit protein eL40)] antibody

UniProt: P62987

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation