p53 anticorps (AA 1-391)
Aperçu rapide pour p53 anticorps (AA 1-391) (ABIN7178833)
Antigène
Voir toutes p53 (TP53) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-391
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Fonction
- Tp53 Antibody
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Réactivité croisée
- Souris, Rat
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Rat Cellular tumor antigen p53 protein (1-391AA)
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Isotype
- IgG
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anti-Tumor Protein P53 (TP53) (pSer392) antibody
TP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (N-Term) antibodyTP53 Reactivité: Humain WB, IF, IHC (p), IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyKO Validated TP53 Reactivité: Humain WB, IF, IHC (p), IP, ICC, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 301-393) antibodyTP53 Reactivité: Humain, Souris, Rat, Chévre WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 293-322) antibodyTP53 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB7777 unconjugated
anti-Tumor Protein P53 (TP53) (pSer20) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (acLys319) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (pSer15) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (pSer33) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyTP53 Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Autre désignation
- Tp53
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Sujet
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Background: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression By similarity. Interacts with GRK5
Aliases: Tp53 antibody, P53 antibody, Cellular tumor antigen p53 antibody, Tumor suppressor p53 antibody
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UniProt
- P10361
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Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
Antigène
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