MCM5 anticorps

N° du produit ABIN7181928

Détail du produit anti-MCM5 anticorps

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from Human MCM5 antibody.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5 (MCM5 Produits)

Synonymes: anticorps 23.m06024, anticorps cdc46, anticorps xmcm5, anticorps CDC46, anticorps P1-CDC46, anticorps Afu5g02520, anticorps NCU01171.1, anticorps AA617332, anticorps AI324988, anticorps AL033333, anticorps Cdc46, anticorps Mcmd5, anticorps mCD46, anticorps mCDC46, anticorps mcm5, anticorps wu:fb34a06, anticorps CG4082, anticorps DmCDC46, anticorps DmCDC465, anticorps DmMCM5, anticorps DmMcm5, anticorps DmeMCM5, anticorps Dmel\\CG4082, anticorps MCM5, anticorps McM5, anticorps PCR4, anticorps DNA replication licensing factor MCM5, anticorps minichromosome maintenance complex component 5 S homeolog, anticorps minichromosome maintenance complex component 5, anticorps DNA replication licensing factor Mcm5, anticorps DNA replication licensing factor mcm5, anticorps MCM5 minichromosome maintenance deficient 5 (S. cerevisiae), anticorps minichromosome maintenance complex component 5 L homeolog, anticorps Minichromosome maintenance 5, anticorps DNA replication licensing factor mcm-5, anticorps BBOV_IV010040, anticorps mcm5.S, anticorps MCM5, anticorps AFUA_5G02520, anticorps NCU01171, anticorps PVX_084615, anticorps LOC5576119, anticorps CpipJ_CPIJ008678, anticorps Bm1_24480, anticorps CMU_022890, anticorps Mcm5, anticorps mcm5, anticorps TP01_0722, anticorps mcm5.L, anticorps mcm-5

Sujet:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity By similarity. Interacts with MCMBP.

Robert A. Sclafani, Genetics, May 2002, 161: 47.
Marylynn Snyder, PNAS, Oct 2005, 102: 14539 - 14544.
Christopher J. DaFonseca, PNAS, Mar 2001, 98: 3034.
Cathleen M. Lake, Genetics, Jun 2007, 10.1534

Aliases: CDC 46 antibody, CDC46 antibody, CDC46 homolog antibody, Cell division cycle 46 antibody, DNA replication licensing factor antibody, DNA replication licensing factor MCM 5 antibody, DNA replication licensing factor MCM5 antibody, MCM 5 antibody, MCM5 antibody, MCM5_HUMAN antibody, MGC5315 antibody, Minichromosome maintenance complex component 5 antibody, Minichromosome maintenance deficient (S. cerevisiae) 5 antibody, Minichromosome maintenance deficient 5 antibody, Minichromosome maintenance deficient protein 5 antibody, P1 CDC46 antibody, P1-CDC46 antibody

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA