SCN5A anticorps
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- Antigène Voir toutes SCN5A Anticorps
- SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SCN5A est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from Human sodium channel.
- Isotype
- IgG
- Top Product
- Discover our top product SCN5A Anticorps primaire
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- Indications d'application
- WB:1:500-1:3000, IHC:1:50-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))
- Autre désignation
- SCN5A (SCN5A Produits)
- Synonymes
- anticorps Nav1.5, anticorps Nav1.5c, anticorps SkM1, anticorps SkM2, anticorps mH1, anticorps CDCD2, anticorps CMD1E, anticorps CMPD2, anticorps HB1, anticorps HB2, anticorps HBBD, anticorps HH1, anticorps ICCD, anticorps IVF, anticorps LQT3, anticorps PFHB1, anticorps SSS1, anticorps VF1, anticorps SCAL, anticorps sodium voltage-gated channel alpha subunit 5, anticorps sodium channel, voltage-gated, type V, alpha, anticorps SCN5A, anticorps Scn5a
- Sujet
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Background: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.
Sebastian K.G. Maier, Circulation, Mar 2004, 109: 1421 - 1427.
T.R. Cummins, Neurology, Jan 2003, 60: 224 - 229.
Christopher A. Ahern, Circ. Res., May 2005, 96: 991 - 998.
Jyoti Dhar Malhotra, Circulation, Mar 2001, 103: 1303 - 1310.Aliases: Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit antibody, CDCD2 antibody, CMD1E antibody, CMPD2 antibody, HB1 antibody, HB2 antibody, HBBD antibody, HH1 antibody, ICCD antibody, IVF antibody, LQT3 antibody, PFHB1 antibody, Scn5a (gene name) antibody, Scn5a antibody, SCN5A_HUMAN antibody, Sodium channel protein cardiac muscle alpha subunit antibody, Sodium channel protein cardiac muscle subunit alpha antibody, Sodium channel protein type 5 subunit alpha antibody, Sodium channel protein type V alpha subunit antibody, Sodium channel protein type V subunit alpha antibody, SSS1 antibody, VF1 antibody, Voltage gated sodium channel alpha subunit Nav1.5 antibody, Voltage-gated sodium channel subunit alpha Nav1.5 antibody
- UniProt
- Q14524
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