RAD21 anticorps
-
- Antigène Voir toutes RAD21 Anticorps
- RAD21 (RAD21 Homolog (RAD21))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp RAD21 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Humain, Souris
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from internal of Human RAD21.
- Isotype
- IgG
- Top Product
- Discover our top product RAD21 Anticorps primaire
-
-
- Indications d'application
- WB:1:500-1:3000,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- RAD21 (RAD21 Homolog (RAD21))
- Autre désignation
- RAD21 (RAD21 Produits)
- Synonymes
- anticorps rad21, anticorps wu:fb55d02, anticorps wu:fb93f04, anticorps CDLS4, anticorps HR21, anticorps HRAD21, anticorps MCD1, anticorps NXP1, anticorps SCC1, anticorps hHR21, anticorps mKIAA0078, anticorps hr21, anticorps mcd1, anticorps nxp-1, anticorps nxp1, anticorps scc1, anticorps xrad21, anticorps RAD21 cohesin complex component, anticorps RAD21 cohesin complex component a, anticorps RAD21 cohesin complex component L homeolog, anticorps RAD21 cohesin complex component S homeolog, anticorps R-spondin 2, anticorps RAD21, anticorps rad21a, anticorps rad21.L, anticorps Rad21, anticorps rad21.S, anticorps RSPO2
- Sujet
-
Background: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
McKay M.J., Genomics 36:305-315(1996).
Sadano H., Biochem. Biophys. Res. Commun. 267:418-422(2000).
Nomura N., DNA Res. 1:223-229(1994).Aliases: CDLS4 antibody, Double-strand-break repair protein rad21 homolog antibody, hHR21 antibody, HR21 antibody, HRAD21 antibody, KIAA0078 antibody, MCD1 antibody, Nuclear matrix protein 1 antibody, NXP-1 antibody, NXP1 antibody, Protein involved in DNA double-strand break repair antibody, RAD21 antibody, RAD21 homolog (S. pombe) antibody, RAD21 homolog antibody, RAD21_HUMAN antibody, Scc1 antibody, SCC1 homolog antibody
- UniProt
- O60216
- Pathways
- Positive Regulation of Endopeptidase Activity
-