NFASC anticorps

N° du produit ABIN7191635

Détail du produit anti-NFASC anticorps

Antigène: NFASC (Neurofascin (NFASC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFASC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human NFASC

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NFASC

Antigène: NFASC (Neurofascin (NFASC))

Autre désignation: NFASC (NFASC Produits)

Synonymes: anticorps sc:d0205, anticorps NF, anticorps NRCAML, anticorps AA387016, anticorps D430023G06Rik, anticorps mKIAA0756, anticorps neurofascin, anticorps neurofascin homolog (chicken) a, anticorps NFASC, anticorps nfasca, anticorps Nfasc

Sujet:

Background: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.

Aliases: KIAA0756 antibody, Neurofascin antibody, Neurofascin homolog antibody, NF antibody, Nfasc antibody, NFASC_HUMAN antibody, NRCAML antibody

UniProt: O94856

Pathways: Cell-Cell Junction Organization