NOTCH4 anticorps

N° du produit ABIN7191676

Détail du produit anti-NOTCH4 anticorps

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human NOTCH4

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NOTCH4

Antigène: NOTCH4 (Notch 4 (NOTCH4))

Autre désignation: NOTCH4 (NOTCH4 Produits)

Synonymes: anticorps INT3, anticorps NOTCH3, anticorps Int-3, anticorps Int3, anticorps N4, anticorps Notch4, anticorps notch 4, anticorps neurogenic locus notch homolog protein 4, anticorps NOTCH4, anticorps Notch4, anticorps LOC100712850

Sujet:

Background: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.

Aliases: FLJ16302 antibody, hNotch 4 antibody, hNotch4 antibody, INT3 antibody, Neurogenic locus notch homolog protein 4 antibody, NOTC4_HUMAN antibody, Notch 4 antibody, Notch 4 intracellular domain antibody, Notch homolog 4 antibody, Notch4 antibody, NOTCH4 protein antibody

UniProt: Q99466

Pathways: Signalisation Notch