GTPase NRas anticorps

N° du produit ABIN7191712

Cet anticorps Lapin Polyclonal détecte spécifiquement GTPase NRas dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour GTPase NRas anticorps (ABIN7191712)

Antigène: GTPase NRas (NRAS)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTPase NRas est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GTPase NRas anticorps

Fonction: NRAS Antibody

Réactivité croisée: Souris, Rat

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of Human NRAS

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GTPase NRas

Antigène: GTPase NRas (NRAS)

Autre désignation: NRAS

Sujet:

Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Aliases: ALPS4 antibody, AV095280 antibody, GTPase NRas antibody, HRAS1 antibody, N ras antibody, N ras protein part 4 antibody, Neuroblastoma RAS viral (v ras) oncogene homolog antibody, NRAS antibody, NRAS1 antibody, NS6 antibody, OTTHUMP00000013879 antibody, OTTMUSP00000023521 antibody, RASN_HUMAN antibody, Transforming protein N Ras antibody, Transforming protein N-Ras antibody, v ras neuroblastoma RAS viral oncogene homolog antibody

UniProt: P01111

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling