PTPRJ anticorps (AA 36-210)

N° du produit ABIN7193256

Détail du produit anti-PTPRJ anticorps

Antigène: PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))

Épitope: AA 36-210

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTPRJ est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CD148 (AA: extra 36-210) expressed in E. coli.

Clone: 1D2C11

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur PTPRJ

Antigène: PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))

Autre désignation: CD148 (PTPRJ Produits)

Synonymes: anticorps HAAP, anticorps CD148, anticorps DEP1, anticorps HPTPeta, anticorps R-PTP-ETA, anticorps SCC1, anticorps AI450271, anticorps BET, anticorps Byp, anticorps DEP-1, anticorps PTPbeta2, anticorps Ptpb2, anticorps RPTPJ, anticorps Scc-1, anticorps Scc1, anticorps PTPRJ, anticorps acid phosphatase 1, anticorps protein tyrosine phosphatase, receptor type J, anticorps protein tyrosine phosphatase, receptor type, J, anticorps ACP1, anticorps PTPRJ, anticorps Ptprj, anticorps EUBREC_2762

Sujet:

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: PTPRJ, DEP1, SCC1, HPTPeta, R-PTP-ETA

Poids moléculaire: 146 kDa

ID gène: 5795

Pathways: EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling