Parkin anticorps (AA 1-144)

N° du produit ABIN7193428

Détail du produit anti-Parkin anticorps

Antigène: Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))

Épitope: AA 1-144

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Parkin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human PRKN (AA: 1-144) expressed in E. coli.

Clone: 6F5D2

Isotype: IgG2a

Information d'application

Indications d'application: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur Parkin

Antigène: Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))

Autre désignation: PRKN (PARK2 Produits)

Synonymes: anticorps CG10523, anticorps Dmel\\CG10523, anticorps Dpark, anticorps SD01679, anticorps dpk, anticorps AR-JP, anticorps LPRS2, anticorps PDJ, anticorps PRKN, anticorps Park, anticorps Prkn, anticorps si:ch211-123f21.1, anticorps zgc:112390, anticorps pdr-1, anticorps PARK2, anticorps parkin, anticorps parkin RBR E3 ubiquitin protein ligase, anticorps Parkinson disease (autosomal recessive, juvenile) 2, parkin, anticorps park, anticorps PRKN, anticorps Prkn, anticorps prkn, anticorps CpipJ_CPIJ014867, anticorps Park2

Sujet:

Description: The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Aliases: PDJ, AR-JP, LPRS2, PARK2

Poids moléculaire: 51.6 kDa

ID gène: 5071

Pathways: Autophagy, Ubiquitin Proteasome Pathway