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APEX2 anticorps (AA 1-180)

APEX2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7265632
  • Antigène Voir toutes APEX2 Anticorps
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    Épitope
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-180
    Reactivité
    • 20
    • 2
    • 1
    Humain
    Hôte
    • 20
    • 2
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp APEX2 est non-conjugé
    Application
    • 20
    • 15
    • 15
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    APEX2 Rabbit pAb
    Séquence
    MLRVVSWNIN GIRRPLQGVA NQEPSNCAAV AVGRILDELD ADIVCLQETK VTRDALTEPL AIVEGYNSYF SFSRNRSGYS GVATFCKDNA TPVAAEEGLS GLFATQNGDV GCYGNMDEFT QEELRALDSE GRALLTQHKI RTWEGKEKTL TLINVYCPHA DPGRPERLVF KMRFYRLLQI
     Réactivité croisée
    Humain
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APEX2 (NP_055296.2).
    Isotype
    IgG
    Top Product
    Discover our top product APEX2 Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    Autre désignation
    APEX2 (APEX2 Produits)
    Synonymes
    anticorps APE2, anticorps APEXL2, anticorps XTH2, anticorps ape2, anticorps apexl2, anticorps xth2, anticorps zgc:55889, anticorps C430040P13Rik, anticorps apurinic/apyrimidinic endodeoxyribonuclease 2, anticorps APEX nuclease (apurinic/apyrimidinic endonuclease) 2, anticorps apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog, anticorps apurinic/apyrimidinic endonuclease 2, anticorps APEX2, anticorps apex2, anticorps apex2.L, anticorps Apex2
    Sujet
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,APEX2;APE2;APEXL2;XTH2;ZGRF2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,APEX2
    Poids moléculaire
    57kDa
    ID gène
    27301
    UniProt
    Q9UBZ4
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