CARD16 anticorps (AA 50-150)

N° du produit ABIN7266127

Détail du produit anti-CARD16 anticorps

Antigène: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Épitope: AA 50-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD16 est non-conjugé

Application: Western Blotting (WB)

Fonction: CARD16 Rabbit pAb

Séquence: VMDKTRALID SVIPKGAQAC QICITYICEE DSYLAETLGL SAALQAVQDN PAMPTCSSPE GRIKLCFLED AQRIWKQKLQ RCHVQNTIIK WSERYTSGSF E

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CARD16 (NP_001017534.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CARD16

Antigène: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Autre désignation: CARD16 (CARD16 Produits)

Synonymes: anticorps COP, anticorps COP1, anticorps PSEUDO-ICE, anticorps caspase recruitment domain family member 16, anticorps CARD16

Sujet: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.,CARD16,COP,COP1,PSEUDO-ICE,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD16

Poids moléculaire: 10kDa/22kDa

ID gène: 114769

UniProt: Q5EG05