anticorps COX4, anticorps COX4-1, anticorps COXIV, anticorps mg:bb02d03, anticorps zgc:110058, anticorps GB20012, anticorps AL024441, anticorps Cox4, anticorps Cox4a, anticorps cox4, anticorps cox4i1, anticorps coxiv, anticorps BcDNA:AT07685, anticorps CG10396, anticorps COX IV, anticorps CX41, anticorps CX42, anticorps Dmel\CG10396, anticorps IV, anticorps cytochrome c oxidase subunit 4I1, anticorps cytochrome c oxidase subunit IV isoform 1, anticorps cytochrome c oxidase subunit 4 isoform 1, mitochondrial, anticorps cytochrome c oxidase polypeptide IV, anticorps cytochrome c oxidase subunit IV, anticorps cytochrome c oxidase subunit 4i1, anticorps cytochrome c oxidase subunit IV isoform 1 S homeolog, anticorps Cytochrome c oxidase subunit 4-like, anticorps COX4I1, anticorps cox4i1, anticorps LOC412396, anticorps Cox4I1, anticorps LOC780848, anticorps BMEII0322, anticorps RSal33209_1582, anticorps SJAG_00976, anticorps HMPREF0733_11926, anticorps Cox4i1, anticorps cox4i1.S, anticorps COX4L
Sujet
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],COX IV-1, COX4, COX4-1, COXIV, COXIV-1,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Mitochondrial metabolism_Oxidative phosphorylation,Neurodegenerative Diseases,Neuroscience,Signal Transduction,COX4I1