HAP1 anticorps (AA 1-240)

N° du produit ABIN7267795

Détail du produit anti-HAP1 anticorps

Antigène: HAP1 (Huntingtin Associated Protein 1 (HAP1))

Épitope: AA 1-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAP1 est non-conjugé

Application: Western Blotting (WB)

Fonction: HAP1 Rabbit pAb

Séquence: MRPKRLGRCC AGSRLGPGDP AALTCAPSPS ASPAPEPSAQ PQARGTGQRV GSRATSGSQF LSEARTGARP ASEAGAKAGA RRPSAFSAIQ GDVRSMPDNS DAPWTRFVFQ GPFGSRATGR GTGKAAGIWK TPAAYVGRRP GVSGPERAAF IRELEEALCP NLPPPVKKIT QEDVKVMLYL LEELLPPVWE SVTYGMVLQR ERDLNTAARI GQSLVKQNSV LMEENSKLEA LLGSAKEEIL

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HAP1 (NP_817084.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HAP1

Antigène: HAP1 (Huntingtin Associated Protein 1 (HAP1))

Autre désignation: HAP1 (HAP1 Produits)

Synonymes: anticorps HAP2, anticorps HIP5, anticorps HLP, anticorps hHLP1, anticorps HAP1-A, anticorps HAP1-B, anticorps HAP-1, anticorps huntingtin associated protein 1, anticorps huntingtin-associated protein 1, anticorps HAP1, anticorps Hap1

Sujet: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.,HAP1;HAP2;HIP5;HLP;hHLP1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,HAP1

Poids moléculaire: 66kDa/67kDa/69kDa/75kDa

ID gène: 9001

UniProt: P54257

Pathways: Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus