MTOR anticorps (pSer2448)

N° du produit ABIN7268435

L’anticorps Lapin Monoclonal anti-MTOR a été validé pour WB. Il convient pour détecter MTOR dans des échantillons de Humain.

Aperçu rapide pour MTOR anticorps (pSer2448) (ABIN7268435)

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MTOR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MTOR anticorps

Épitope: pSer2448

Fonction: Phospho-mTOR-S2448 Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Phospho-mTOR (S2448).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MTOR

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Autre désignation: mTOR

Sujet: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008],FRAP,FRAP1,FRAP2,RAFT1,RAPT1,SKS,mTOR,MTOR,AMPK Signaling Pathway,Angiogenesis,Autophagy,Autophagy_Regulator,B Cell Receptor Signaling Pathway,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,DNA Damage & Repair,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Obesity,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Heart,Heart_Cardiogenesis,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Insulin Receptor Signaling Pathway,Kinase,Kinase_Serine/threonine kinases,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,Protein phosphorylation,Signal Transduction,T Cell Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Transcription Factors,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,Warburg Effect,mTOR

Poids moléculaire: 289kDa

ID gène: 2475

UniProt: P42345

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, L'effet Warburg