GANP anticorps (AA 250-550)

N° du produit ABIN7268541

Détail du produit anti-GANP anticorps

Antigène: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Épitope: AA 250-550

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GANP est non-conjugé

Application: Western Blotting (WB)

Fonction: MCM3AP Rabbit pAb

Séquence: SSFPVSSAVL GEPFQASKAG VRQGCEEAVS QVEPLPSLMK GLKRKEDQDR SPRRHGHEPA EDSDPLSRGD HPPDKRPVRL NRPRGGTLFG RTIQDVFKSN KEVGRLGNKE AKKETGFVES AESDHMAIPG GNQSVLAPSR IPGVNKEEET ESREKKEDSL RGTPARQSNR SESTDSLGGL SPSEVTAIQC KNIPDYLNDR TILENHFGKI AKVQRIFTRR SKKLAVVHFF DHASAALARK KGKSLHKDMA IFWHRKKISP NKKPFSLKEK KPGDGEVSPS TEDAPFQHSP LGKAAGRTGA S

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human MCM3AP (NP_003897.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GANP

Antigène: GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))

Autre désignation: MCM3AP (MCM3AP Produits)

Synonymes: anticorps GANP, anticorps MAP80, anticorps SAC3, anticorps mKIAA0572, anticorps minichromosome maintenance complex component 3 associated protein, anticorps germinal-center associated nuclear protein, anticorps Mcm3ap, anticorps MCM3AP, anticorps mcm3ap, anticorps LOC100026233

Sujet: The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.,MCM3AP,GANP,MAP80,SAC3,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cell differentiation,MCM3AP

Poids moléculaire: 80kDa/218kDa

ID gène: 8888

UniProt: O60318

Pathways: Protein targeting to Nucleus