RANBP2 anticorps

N° du produit ABIN7269843

Détail du produit anti-RANBP2 anticorps

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANBP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: RANBP2 Rabbit pAb

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human RANBP2.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RANBP2

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Autre désignation: RANBP2 (RANBP2 Produits)

Synonymes: anticorps ANE1, anticorps IIAE3, anticorps NUP358, anticorps TRP1, anticorps TRP2, anticorps A430087B05Rik, anticorps AI256741, anticorps RGD1560047, anticorps RANBP2, anticorps ane1, anticorps nup358, anticorps trp1, anticorps trp2, anticorps RAN binding protein 2, anticorps E3 SUMO-protein ligase RanBP2, anticorps RANBP2, anticorps Ranbp2, anticorps LOC474539, anticorps ranbp2, anticorps LOC100511376

Sujet: RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008],ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Signal Transduction,Ubiquitin,RANBP2

ID gène: 5903

UniProt: P49792

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus