DCUN1D1 anticorps (AA 101-200)

N° du produit ABIN717551

Détail du produit anti-DCUN1D1 anticorps

Antigène: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Épitope: AA 101-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCUN1D1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DCUN1D1

Antigène: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Autre désignation: SCRO (DCUN1D1 Produits)

Synonymes: anticorps fd19a01, anticorps zgc:66414, anticorps wu:fd19a01, anticorps dcun1l1, anticorps rp42, anticorps sccro, anticorps scro, anticorps tes3, anticorps DCNL1, anticorps DCUN1L1, anticorps RP42, anticorps SCCRO, anticorps SCRO, anticorps Tes3, anticorps Rp42, anticorps pTes3, anticorps DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae), anticorps DCN1-like protein 1, anticorps DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog, anticorps defective in cullin neddylation 1 domain containing 1, anticorps dcun1d1, anticorps dcnl1, anticorps dcun1d1.L, anticorps DCUN1D1, anticorps Dcun1d1

Sujet:

Synonyms: DCN1 defective in cullin neddylation 1 domain containing 1, DCN1 like protein 1, DCUN1 domain containing protein 1, DCUN1L1, Defective in cullin neddylation protein 1 like protein 1, RP 42, RP42, RP42 homolog, SCCRO, SCRO, Squamous cell carcinoma related oncogene, Tes 3, Tes3.

Background: DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.

ID gène: 54165