JAK2 anticorps (AA 1082-1132)

N° du produit ABIN7448611

Cet anticorps Lapin Polyclonal détecte spécifiquement JAK2 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour JAK2 anticorps (AA 1082-1132) (ABIN7448611)

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK2 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-JAK2 anticorps

Épitope: AA 1082-1132

Fonction: Rabbit anti-JAK2 IHC Antibody, Affinity Purified

Homologie: Dog,Horse,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Naked mole rat,Ferret

Purification: Affinity Purified

Immunogène: Between AA 1082 and 1132

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur JAK2

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Autre désignation: JAK2

Sujet: Background: JAK2 (Janus kinase 2) was originally cloned via screening of mouse cDNA libraries with PCR generated probes representing highly conserved elements in the protein tyrosine kinase (PTK) family. JAK2, as well as JAK, was named after the Roman god, Janus, the god of gates or doors, and who is depicted as having two faces which face opposite directions. JAK kinases bear two nearly identical phosphate transferring domains and function to transduce signals from type I and type II cytokine receptors for the activation of STAT (signal transducers and activators of transcription) transcription factors.

ID gène: 3717

NCBI Accession: NP_004963

UniProt: O60674

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response