TCEB2 anticorps (AA 68-118)

N° du produit ABIN7453458

Détail du produit anti-TCEB2 anticorps

Antigène: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Épitope: AA 68-118

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCEB2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-TCEB2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 68 and 118

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TCEB2

Antigène: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Autre désignation: TCEB2 (TCEB2 Produits)

Synonymes: anticorps 0610040H15Rik, anticorps cb162, anticorps wu:fb47e08, anticorps ELOB, anticorps SIII, anticorps elongin B, anticorps Elob, anticorps elob, anticorps ELOB

Sujet: Background: TCEB2, also known as Elongin B, is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation [taken from NCBI Entrez Gene (Gene ID: 6923)].

ID gène: 6923

NCBI Accession: NP_009039

UniProt: Q15370

Pathways: SARS-CoV-2 Protein Interactome