p53 anticorps (AA 20-25)
Aperçu rapide pour p53 anticorps (AA 20-25) (ABIN7455068)
Antigène
Voir toutes p53 (TP53) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 20-25
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Fonction
- Mouse anti-p53 Monoclonal Antibody Purified [DO-1]
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Purification
- Purified
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Immunogène
- Recombinant full length protein corresponding to Human p53 (N terminal). epitope is within aa 20-25
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Isotype
- IgG2a
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anti-Tumor Protein P53 (TP53) (pSer392) antibody
TP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyKO Validated TP53 Reactivité: Humain WB, IF, IHC (p), IP, ICC, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (N-Term) antibodyTP53 Reactivité: Humain WB, IF, IHC (p), IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reactivité: Humain WB, ELISA, IF, IHC (p), IP Hôte: Souris Monoclonal 2C3 unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reactivité: Humain WB, ELISA, IHC (p), PLA, RNAi Hôte: Souris Monoclonal 2C11 unconjugated
anti-Tumor Protein P53 (TP53) (pSer20) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (acLys319) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (pSer15) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 301-393) antibodyTP53 Reactivité: Humain, Souris, Rat, Chévre WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyTP53 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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IHC: 1:50 - 1:200. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 20 μL/mg lysate
WB: 17:40:00
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2 - 8 °C
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Date de péremption
- 12 months
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Autre désignation
- p53
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Sujet
- P53 is a tumor suppressor protein that is mutated or inactivated in over 50 % of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis.
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ID gène
- 7157
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UniProt
- P04637
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Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
Antigène
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