Recombinant TP53BP1 anticorps (AA 350-400)

N° du produit ABIN7455070

L’anticorps Lapin Monoclonal anti-TP53BP1 a été validé pour WB, IP et IHC (fp). Il convient pour détecter TP53BP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant TP53BP1 anticorps (AA 350-400) (ABIN7455070)

Antigène: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TP53BP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BL-250-1H11

Détail du produit anti-TP53BP1 anticorps

Épitope: AA 350-400

Fonction: Rabbit anti-53BP1 Recombinant Monoclonal Antibody [BL-250-1H11]

Immunogène: between AA 350 and 400

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/mg lysate

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TP53BP1

Antigène: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Autre désignation: 53BP1

Sujet: Background: 53BP1 (p53 Binding Protein 1) is an early participant in the cellular response to DNA double-strand breaks. 53BP1 functions in a redundant role in phosphorylation of the downstream checkpoint effector proteins Brca1 and Chk2 but was required for the formation of Brca1 foci in a hierarchical branched pathway for the recruitment of repair and signaling proteins to sites of DNA damage.

ID gène: 7158

NCBI Accession: NP_005648

UniProt: Q12888

Pathways: Réparation de l'ADN