ATP6V1B2 anticorps

N° du produit ABIN7468018

Détail du produit anti-ATP6V1B2 anticorps

Antigène: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V1B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ATP6V1B2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , mouse brain , rat brain Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ATP6V1B2

Antigène: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Autre désignation: ATPase H+ transporting V1 subunit B2 (ATP6V1B2 Produits)

Synonymes: anticorps Atp6b1b2, anticorps Atp6b2, anticorps Vatb, anticorps vha55, anticorps VATB, anticorps ATP6B1B2, anticorps ATP6B2, anticorps HO57, anticorps VPP3, anticorps Vma2, anticorps atp6v1bb, anticorps fj51e01, anticorps vatB2, anticorps wu:fj51e01, anticorps zgc:109771, anticorps AI194269, anticorps AI790362, anticorps R74844, anticorps ATPase H+ transporting V1 subunit B2, anticorps ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog, anticorps ATPase, H+ transporting, lysosomal, V1 subunit B2, anticorps ATPase, H+ transporting, lysosomal V1 subunit B2, anticorps Atp6v1b2, anticorps atp6v1b2.S, anticorps ATP6V1B2, anticorps atp6v1b2

Sujet:

Synonyms: ATPase H+ transporting V1 subunit B2 , ATP6B1B2 , ATP6B2 , DOOD , HO57 , VATB , VPP3 , Vma2 , ZLS2

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]

Poids moléculaire: 57 kDa

ID gène: 526

UniProt: P21281

Pathways: Transition Metal Ion Homeostasis, Proton Transport