DICER1 anticorps (AA 1301-1400) (HRP)
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- Antigène Voir toutes DICER1 Anticorps
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
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Épitope
- AA 1301-1400
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DICER1 est conjugé à/à la HRP
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain
- Homologie
- Mouse,Rat,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DICER1
- Isotype
- IgG
- Top Product
- Discover our top product DICER1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
- Autre désignation
- DICER1 (DICER1 Produits)
- Synonymes
- anticorps dcr1, anticorps dicer, anticorps herna, anticorps DICER1, anticorps dicer1, anticorps 1110006F08Rik, anticorps D12Ertd7e, anticorps mKIAA0928, anticorps DCR1, anticorps Dicer, anticorps HERNA, anticorps MNG1, anticorps DICER, anticorps fc39d11, anticorps fc74b05, anticorps wu:fc39d11, anticorps wu:fc74b05, anticorps dicer 1, ribonuclease III, anticorps endoribonuclease Dicer, anticorps dicer 1, ribonuclease III S homeolog, anticorps dicer 1, ribonuclease type III, anticorps dicer 1 ribonuclease III, anticorps DICER1, anticorps CpipJ_CPIJ010534, anticorps dicer1, anticorps dicer1.S, anticorps Dicer1
- Sujet
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Synonyms: DCR1, MNG1, Dicer, HERNA, RMSE2, Dicer1e, K12H4.8-LIKE, Endoribonuclease Dicer, Helicase with RNase motif, Helicase MOI, DICER1, KIAA0928
Background: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.
- ID gène
- 23405
- UniProt
- Q9UPY3
- Pathways
- Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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