Recombinant Insulin anticorps

N° du produit ABIN7543283

Cet anticorps Souris Monoclonal détecte spécifiquement Insulin dans ELISA, FACS et RIA. Il présente une réactivité envers Boeuf (Vache).

Aperçu rapide pour Recombinant Insulin anticorps (ABIN7543283)

Antigène: Insulin (INS)

Type d'anticorp: Recombinant Antibody

Reactivité: Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Radioimmunoassay (RIA)

Clone: Ab 123

Détail du produit anti-Insulin anticorps

Fonction: Anti-Insulin [Ab 123 (mAb3, CC9C10)], Mouse IgG1, kappa

Specificité: This antibody binds an epitope on the B chain of calf, human and rodent insulin. Insulin is a peptide hormone produced by the beta cells of the pancreatic islets. It reduces blood glucose concentration by promoting its absorption from the blood into liver, fat and skeletal muscle cells. Decreased or absent insulin activity results in diabetes mellitus, a condition of high blood sugar level (hyperglycemia).

Réactivité croisée: Humain, Rongeurs

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: The original antibody was generated by immunizing female BALB/c mice with calf insulin in Freund's complete adjuvant.

Isotype: IgG1 kappa

Information d'application

Indications d'application: This antibody can be used to detect insulin in a sample using ELISA and radioimmunoassay (PMID: 2109009, 6193965). This antibody was used in the flow cytometric analysis of insulin occupied B cell receptors in VH125SD B6 mice (PMID: 26109644).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Insulin

Antigène: Insulin (INS)

Autre désignation: Insulin

Sujet: INS, proinsulin

UniProt: P01317

Pathways: Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation