EIF2AK2 anticorps (pThr446)

N° du produit ABIN7603398

Cet anticorps Lapin Monoclonal détecte spécifiquement EIF2AK2 dans WB, IHC et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour EIF2AK2 anticorps (pThr446) (ABIN7603398)

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF2AK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: BIC-5

Détail du produit anti-EIF2AK2 anticorps

Épitope: pThr446

Fonction: Anti-Phospho-PKR (T446) EIF2AK2 Rabbit Monoclonal Antibody

Attributs du produit: Anti-Phospho-PKR EIF2AK2 Rabbit Monoclonal Antibody (ABIN7603398). Tested in WB, IHC, IP applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Phospho-PKR (T446)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:50-1:200
IP 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur EIF2AK2

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: EIF2AK2

Sujet:

Synonyms: Interferon-induced, double-stranded RNA-activated protein kinase,2.7.11.1,Eukaryotic translation initiation factor 2-alpha kinase 2,eIF-2A protein kinase 2,Interferon-inducible RNA-dependent protein kinase,P1/eIF-2A protein kinase,Protein kinase RNA-activated,PKR,Protein kinase R ,Tyrosine-protein kinase EIF2AK2,2.7.10.2,p68 kinase,EIF2AK2,PKR, PRKR,

Tissue Specificity: Highly expressed in thymus, spleen and bone marrow compared to non-hematopoietic tissues such as small intestine, liver, or kidney tissues. Colocalizes with GSK3B and TAU in the Alzheimer disease (AD) brain. Elevated levels seen in breast and colon carcinomas,and which correlates with tumor progression and invasiveness or risk of progression. .

Poids moléculaire: 39 kDa

UniProt: P19525

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C