LCK anticorps

N° du produit ABIN7605414

Cet anticorps Lapin Monoclonal détecte spécifiquement LCK dans WB, IHC, IF, FACS, IP et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour LCK anticorps (ABIN7605414)

Antigène: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LCK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: ADBE-12

Détail du produit anti-LCK anticorps

Fonction: Anti-Lck Monoclonal Antibody

Attributs du produit: Anti-Lck Monoclonal Antibody (ABIN7605414). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Lck The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:80
FC 1:20

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur LCK

Antigène: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Autre désignation: LCK

Sujet:

Synonyms: Prolyl endopeptidase FAP ,3.4.21.26 ,170 kDa melanoma membrane-bound gelatinase ,Dipeptidyl peptidase FAP ,3.4.14.5 ,Fibroblast activation protein alpha ,FAPalpha ,Gelatine degradation protease FAP ,3.4.21.- ,Integral membrane serine protease ,Post-proline cleaving enzyme ,Serine integral membrane protease ,SIMP ,Surface-expressed protease ,Seprase ,Antiplasmin-cleaving enzyme FAP, soluble form ,APCE ,3.4.14.5 ,3.4.21.- ,3.4.21.26 ,FAP ,

Tissue Specificity: Expressed in adipose tissue. Expressed in the dermal fibroblasts in the fetal skin. Expressed in the granulation tissue of healing wounds and on reactive stromal fibroblast in epithelial cancers. Expressed in activated fibroblast-like synoviocytes from inflamed synovial tissues. Expressed in activated hepatic stellate cells (HSC) and myofibroblasts from cirrhotic liver, but not detected in normal liver. Expressed in glioma cells (at protein level). Expressed in glioblastomas and glioma cells. Isoform 1 and isoform 2 are expressed in melanoma, carcinoma and fibroblast cell lines. .

Poids moléculaire: 11 kDa

UniProt: P06239

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling