Recombinant MTOR anticorps (pSer2448)

N° du produit ABIN7799348

Cet anticorps Lapin Monoclonal détecte spécifiquement MTOR dans WB, FACS, ICC et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant MTOR anticorps (pSer2448) (ABIN7799348)

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MTOR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Classe de qualité: KD Validated

Clone: 24GB330

Détail du produit anti-MTOR anticorps

Épitope: pSer2448

Expression System: HEK-293 Cells

Fonction: KD-Validated Phospho-mTOR (S2448) Recombinant Rabbit mAb

Réactivité croisée: Souris, Rat

Purification: Affinity Purified

Immunogène: A synthesized peptide derived from human Phospho-mTOR (S2448)

Isotype: IgG

Information d'application

Indications d'application: Western Blotting (WB): 1:1,000-1:5,000, Flow Cytometry (FCM): 1:200-1:2,000, Immunocytochemistry (ICC): 1:100-1:1,000, Immunohistochemistry-Paraffin (IHC-P): 1:100-1:200

Commentaires:

We assess the antibodies’ specificity and selectivity using knockdown techniques. Our validation approach is straightforward: if an antibody identifies a signal in wild-type (WT) cells, but this signal is absent or noticeably reduced in gene-silenced (KD) cells, we consider the antibody to be highly specific.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C for one year.

Date de péremption: 12 months

Détails sur MTOR

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Autre désignation: mTOR

Poids moléculaire: 289 kDa

ID gène: 2475

UniProt: P42345

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, L'effet Warburg