Recombinant PDK2 anticorps

N° du produit ABIN7828509

Cet anticorps anti-PDK2 Monoclonal Lapin (Clone A433) (ABIN7828509) détecte spécifiquement PDK2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant PDK2 anticorps (ABIN7828509)

Antigène: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PDK2 est non-conjugé

Application: Western Blotting (WB)

Clone: A433

Détail du produit anti-PDK2 anticorps

Fonction: Recombinant PDK2 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human PDK2 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000-1:10000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PDK2

Antigène: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Autre désignation: PDK2

Sujet: PDK,PDHK,Pyruvate dehydrogenase kinase isoform,Pyruvate dehydrogenase lipoamide kinase isozyme,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme,isozyme,PDK2,PDHK2,PDKII,[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2,isozyme 2,mitochondrial,Pyruvate dehydrogenase kinase,Pyruvate dehydrogenase kinase isoform 2,Pyruvate dehydrogenase lipoamide kinase isozyme 2,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 46 kDa

Observed MW: 46 kDa

UniProt: Q15119

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg