Recombinant p53 anticorps (full length)
Aperçu rapide pour Recombinant p53 anticorps (full length) (ABIN7879256)
Antigène
Voir toutes p53 (TP53) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- Recombinant TP53 Antibody / p53 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- Recombinant full-length human protein was used as the immunogen for the recombinant TP53 antibody.
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Isotype
- IgG1, kappa
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anti-Tumor Protein P53 (TP53) (pSer392) antibody
TP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyKO Validated TP53 Reactivité: Humain WB, IF, IHC (p), IP, ICC, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (N-Term) antibodyTP53 Reactivité: Humain WB, IF, IHC (p), IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reactivité: Humain WB, ELISA, IF, IHC (p), IP Hôte: Souris Monoclonal 2C3 unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reactivité: Humain WB, ELISA, IHC (p), PLA, RNAi Hôte: Souris Monoclonal 2C11 unconjugated
anti-Tumor Protein P53 (TP53) (pSer20) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (acLys319) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (pSer15) antibodyTP53 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 301-393) antibodyTP53 Reactivité: Humain, Souris, Rat, Chévre WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyTP53 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal dilution of the recombinant TP53 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the recombinant TP53 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Autre désignation
- TP53
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Sujet
- Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. It is a tumor suppressor protein expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast, lung, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in many malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
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UniProt
- P04637
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Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
Antigène
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