GTPase NRas anticorps

N° du produit ABIN7880942

Cet anticorps Lapin Monoclonal détecte spécifiquement GTPase NRas dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GTPase NRas anticorps (ABIN7880942)

Antigène: GTPase NRas (NRAS)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GTPase NRas est non-conjugé

Application: Western Blotting (WB)

Clone: AOFE-14

Détail du produit anti-GTPase NRas anticorps

Fonction: NRAS Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human NRAS was used as the immunogen for the NRAS antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the NRAS antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the NRAS antibody at -20oC.

Détails sur GTPase NRas

Antigène: GTPase NRas (NRAS)

Autre désignation: NRAS

Sujet: NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. It has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in the gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [RefSeq]

UniProt: P01111

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling