JAK2 anticorps

N° du produit ABIN7881333

Cet anticorps Lapin Monoclonal détecte spécifiquement JAK2 dans WB, ICC, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour JAK2 anticorps (ABIN7881333)

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp JAK2 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: COG-10

Détail du produit anti-JAK2 anticorps

Fonction: JAK2 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human JAK2 was used as the immunogen for the JAK2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the JAK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the JAK2 antibody at -20oC.

Détails sur JAK2

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Autre désignation: JAK2

Sujet: Tyrosine-protein kinase JAK2 is a non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO), or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. [UniProt]

UniProt: O60674

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response