BCL2L1 anticorps (pThr115) (Cy5.5)

N° du produit ABIN756822

Détail du produit anti-BCL2L1 anticorps (Cy5.5)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Épitope: pThr115

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est conjugé à/à la Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human BCL2L1 around the phosphorylation site of Thr115

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: Bcl-xL (BCL2L1 Produits)

Synonymes: anticorps BCL-XL/S, anticorps BCL2L, anticorps BCLX, anticorps BCLXL, anticorps BCLXS, anticorps Bcl-X, anticorps PPP1R52, anticorps bcl-xL, anticorps bcl-xS, anticorps Bcl(X)L, anticorps Bcl-XL, anticorps Bcl-Xs, anticorps Bcl2l, anticorps BclX, anticorps bcl-x, anticorps Bcl-xl, anticorps Bclx, anticorps bcl-X, anticorps Bcl-xL, anticorps BCL-XL, anticorps BCL2L1, anticorps bcl-XL, anticorps bcl-x(l), anticorps bcl-xl/s, anticorps bcl-xs, anticorps bcl2l, anticorps bclx, anticorps bclxl, anticorps xR11, anticorps bcl-xl, anticorps blp1, anticorps cb1021, anticorps zfBLP1, anticorps BCL2 like 1, anticorps BCL2-like 1, anticorps Bcl2-like 1, anticorps BCL2-like 1 L homeolog, anticorps bcl2-like 1, anticorps BCL2L1, anticorps Bcl2l1, anticorps bcl2l1, anticorps bcl2l1.L

Sujet:

Synonyms: BCLX, BCL2L, BCLXL, BCLXS, Bcl-X, bcl-xL, bcl-xS, PPP1R52, BCL-XL/S, Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1

Background: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.

ID gène: 598

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling