HRAS anticorps (AA 51-150) (Cy3)

N° du produit ABIN763379

L’anticorps anti-HRAS Polyclonal Lapin est utilisé pour la détection de HRAS dans des échantillons de Humain. Il a été validé pour WB, IF (p) et IF (cc).

Aperçu rapide pour HRAS anticorps (AA 51-150) (Cy3) (ABIN763379)

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRAS est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-HRAS anticorps (Cy3)

Épitope: AA 51-150

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HRAS+KRAS

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HRAS

Antigène: HRAS (HRas proto-oncogene, GTPase (HRAS))

Autre désignation: HRAS+KRAS

Sujet:

Synonyms: p21ras, Transforming protein p21, GTPase HRas, GTPase KRas, HRas, HRAS1, KRas, KRAS2, RASH, RASK, RASH_HUMAN, RASK_HUMAN.

Background: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.

ID gène: 3265

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling