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NSMCE2 anticorps (C-Term)
NSMCE2
Reactivité: Humain, Souris, Rat
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-NSMCE2 anticorps
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Antigène
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NSMCE2
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
Épitope
Tous les épitopes à travers NSMCE2 Anticorps.
C-Term
Reactivité
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Humain, Souris, Rat
Hôte
Toutes les hôtes sur NSMCE2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur NSMCE2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NSMCE2 Anticorps
Cet anticorp NSMCE2 est non-conjugé
Application
Tous les applications à travers NSMCE2 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Réactivité croisée (Details)
Species reactivity (tested):Human, Mouse, Rat
Purification
Immunoaffinity Chromatography
Immunogène
15 amino acid peptide near the carboxy terminus of Human MMS21
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C.
Détails sur NSMCE2
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Antigène
NSMCE2
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
Autre désignation
NSMCE2 (NSMCE2 Produits )
Synonymes
anticorps 1110014D18Rik, anticorps AI661537, anticorps RGD1305156, anticorps C8orf36, anticorps MMS21, anticorps NSE2, anticorps ZMIZ7, anticorps Non-SMC element 2, anticorps NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase, anticorps NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog, anticorps Smc5-6 complex non-SMC subunit 2, anticorps Nsmce2, anticorps NSMCE2, anticorps nsmce2.L, anticorps nse2
Sujet
MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression, this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.Synonyms: C8orf36, E3 SUMO-protein ligase NSE2, MMS21
ID gène
286053
NCBI Accession
NP_775956
UniProt
Q96MF7
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