HVCN1 anticorps (C-Term)

N° du produit ABIN783681

Détail du produit anti-HVCN1 anticorps

Antigène: HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HVCN1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antoibody detects HVCN1 / VSOP at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of human HVCN1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur HVCN1

Antigène: HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))

Autre désignation: HVCN1 / VSOP (HVCN1 Produits)

Synonymes: anticorps zgc:92181, anticorps HVCN1, anticorps VSOP, anticorps vsx1, anticorps HV1, anticorps 0610039P13Rik, anticorps AI450555, anticorps BTS, anticorps Vsop, anticorps mVSOP, anticorps RGD1310788, anticorps hydrogen voltage-gated channel 1, anticorps hydrogen voltage gated channel 1 pseudogene, anticorps hydrogen voltage gated channel 1, anticorps voltage-gated hydrogen channel 1, anticorps hydrogen voltage gated channel 1 L homeolog, anticorps hvcn1, anticorps LOC452241, anticorps HVCN1, anticorps Hvcn1, anticorps hvcn1.L

Sujet: HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.Synonyms: HV1, Hydrogen voltage-gated channel 1, Voltage sensor domain-only protein, Voltage-gated hydrogen channel 1

ID gène: 84329

NCBI Accession: NP_001035196

UniProt: Q96D96

Pathways: Proton Transport