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MCL-1 anticorps (AA 121-139)
MCL1
Reactivité: Humain
IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-MCL-1 anticorps
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Antigène
Voir toutes MCL-1 (MCL1) Anticorps
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Épitope
Tous les épitopes à travers MCL-1 Anticorps.
AA 121-139
Reactivité
Toutes les réactivités sur MCL-1 Anticorps
Humain
Hôte
Toutes les hôtes sur MCL-1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur MCL-1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers MCL-1 Anticorps
Cet anticorp MCL-1 est non-conjugé
Application
Tous les applications à travers MCL-1 Anticorps.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody reacts to Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1).
Purification
Immunoaffinity Chromatography
Immunogène
A synthetic peptide corresponding to aa 121-139 of human Mcl-1 Genename: MCL1
Isotype
IgG
Top Product
Discover our top product MCL1 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
10 mM PBS, pH 7.4 containing 1 % BSA as stabilizer and 0,09 % sodium azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Détails sur MCL-1
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Antigène
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Autre désignation
MCL1 (MCL1 Produits )
Synonymes
anticorps BCL2L3, anticorps EAT, anticorps MCL1-ES, anticorps MCL1L, anticorps MCL1S, anticorps Mcl-1, anticorps TM, anticorps bcl2-L-3, anticorps mcl1/EAT, anticorps AW556805, anticorps mcl-1, anticorps fb72f02, anticorps wu:fb70a08, anticorps wu:fb72f02, anticorps zfMLP1, anticorps zfMcl-1a, anticorps zgc:109835, anticorps zgc:109763, anticorps E3, anticorps E3-2, anticorps RNE3, anticorps RNU107, anticorps SNORA63A, anticorps elF-4AII, anticorps MCL1, BCL2 family apoptosis regulator, anticorps myeloid cell leukemia sequence 1, anticorps MCL1, BCL2 family apoptosis regulator a, anticorps MCL1, BCL2 family apoptosis regulator b, anticorps small nucleolar RNA, H/ACA box 63, anticorps MCL1, anticorps Mcl1, anticorps mcl1a, anticorps mcl1b, anticorps SNORA63
Sujet
Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis (5) and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least two distinct isoforms designated Mcl-1L and Mcl-1S. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
ID gène
4170
NCBI Accession
NP_001184249
Pathways
Signalisation MAPK
Vus récemment
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