TFB2M anticorps (Internal Region)

N° du produit ABIN783976

Détail du produit anti-TFB2M anticorps

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TFB2M est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: KHCFGRRSAT VIDH

Specificité: Recognizes TFB2M.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_071761.1. Genename: TFB2M

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TFB2M

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Autre désignation: TFB2M (TFB2M Produits)

Synonymes: anticorps CG3910, anticorps Dmel\\CG3910, anticorps TFB2, anticorps d-TF2BM, anticorps d-mtTFB2, anticorps TFB2M, anticorps sb:cb857, anticorps hkp1, anticorps Hkp1, anticorps mtTFB2, anticorps mitochondrial transcription factor B2, anticorps transcription factor B2, mitochondrial, anticorps mtTFB2, anticorps TFB2M, anticorps tfb2m, anticorps Tfb2m

Sujet: The transcription factors B1 (TFB1M, 607033) and B2 (TFB2M) are necessary for basal transcription of mammalian mitochondrial DNA. Human TFB1M and TFB2M are expressed ubiquitously and can each support promoter-specific mtDNA transcription in a pure recombinant in vitro system containing mitochondrial RNA polymerase and mitochondrial transcription factor A. TFB2M has been found to be at least 1 order of magnitude more active in promoting transcription than TFB1M. Both factors are highly homologous to bacterial rRNA dimethyltransferases, which suggests that an RNA-modifying enzyme has been recruited during evolution to function as a mitochondrial transcription factor.Synonyms: Dimethyladenosine transferase 2 mitochondrial, Hepatitis C virus NS5A-transactivated protein 5, Mitochondrial 12S rRNA dimethylase 2, Mitochondrial transcription factor B2, N'-adenosyl(rRNA) dimethyltransferase 2, NS5ATP5, S-adenosylmethionine-6-N', mtTFB2

ID gène: 216

NCBI Accession: NP_071761