p53 anticorps (N-Term)

N° du produit ABIN870342

Cet anticorps anti-p53 est un anticorps Lapin Monoclonal détectant p53 dans IHC (p). Adapté pour Humain.

Aperçu rapide pour p53 anticorps (N-Term) (ABIN870342)

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp p53 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: M26-A

Détail du produit anti-p53 anticorps

Épitope: AA 46-67, N-Term

Fonction: Anti-p53

Specificité: P53

Immunogène: Peptide derived from N-terminal sequence of human p53. Antibody recognizes the epitope between Ser46 - Pro67.

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: +2 °C to +8 °C

Détails sur p53

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation: p53

Sujet: P53 (tumor supressor protein) is general marker of cell proliferation. Its enhanced expression is in most cases related to cancer (e.g. can be used as a valuable prognostic marker of conventional renal cell carcinoma). This clone is specially produced for IHC-P applications.

UniProt: P04637

Pathways: Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg