SUFUH anticorps (pSer342)

N° du produit ABIN871409

Détail du produit anti-SUFUH anticorps

Antigène: SUFUH (Suppressor of Fused Homolog (SUFUH))

Épitope: pSer342

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUFUH est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.

Purification: Affinity purified

Immunogène: Peptide sequence around phosphorylation site of pSer342 (A-P-S (p) -R-K) derived from Human Sufu. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Références pour anticorps anti-SUFUH (ABIN871409)

Chen, Yue, Xie, Pu, Jin, Cheng: "Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium." dans: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13502-11, (2011) (PubMed).

Détails sur SUFUH

Antigène: SUFUH (Suppressor of Fused Homolog (SUFUH))

Autre désignation: Sufu (SUFUH Produits)

Synonymes: anticorps CG6054, anticorps Dmel\\CG6054, anticorps SU(FU), anticorps SUFU, anticorps Su(Fu), anticorps SuFu, anticorps Sufu, anticorps su(fu), anticorps sufu, anticorps Xsufu, anticorps sufuh, anticorps sufuxl, anticorps PRO1280, anticorps SUFUH, anticorps SUFUXL, anticorps Su(fu), anticorps dre, anticorps fi39e05, anticorps wu:fi39e05, anticorps 2810026F04Rik, anticorps b2b273Clo, anticorps Suppressor of fused, anticorps SUFU negative regulator of hedgehog signaling L homeolog, anticorps SUFU negative regulator of hedgehog signaling, anticorps suppressor of fused homolog (Drosophila), anticorps Su(fu), anticorps sufu.L, anticorps SUFU, anticorps sufu, anticorps Sufu

Sujet: SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)

Poids moléculaire: 54 kDa

ID gène: 51684

NCBI Accession: NP_057253

UniProt: Q9UMX1

Pathways: Signalisation Hedgehog, Tube Formation, Maintenance of Protein Location