MAGED1 anticorps

N° du produit ABIN871634

Détail du produit anti-MAGED1 anticorps

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGED1 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Purification: Affinity purified

Immunogène: Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur MAGED1

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Autre désignation: Melanoma-associated antigen D1 (MAGED1 Produits)

Synonymes: anticorps MAGED1, anticorps DLXIN-1, anticorps NRAGE, anticorps 2810433C11Rik, anticorps 5430405L04Rik, anticorps DXBwg1492e, anticorps Dlixin, anticorps Dlxin-1, anticorps Dlxin1, anticorps MAGE-D1, anticorps mFLJ00163, anticorps Nrage, anticorps MAGE family member D1, anticorps melanoma antigen family D, 1, anticorps melanoma antigen, family D, 1, anticorps MAGED1, anticorps Maged1

Sujet: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

Poids moléculaire: 95 kDa

ID gène: 94275

NCBI Accession: NP_062765

UniProt: Q9QYH6

Pathways: Neurotrophin Signaling Pathway