NCOA3 anticorps (pThr24) (Alexa Fluor 647)

N° du produit ABIN877829

Détail du produit anti-NCOA3 anticorps (Alexa Fluor 647)

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Épitope: pThr24

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA3 est conjugé à/à la Alexa Fluor 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SRC-3 around the phosphorylation site of Thr24

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: Src-3 (NCOA3 Produits)

Synonymes: anticorps NCOA3, anticorps ACTR, anticorps AIB-1, anticorps AIB1, anticorps CAGH16, anticorps CTG26, anticorps KAT13B, anticorps RAC3, anticorps SRC-3, anticorps SRC3, anticorps TNRC14, anticorps TNRC16, anticorps TRAM-1, anticorps bHLHe42, anticorps pCIP, anticorps 2010305B15Rik, anticorps AW321064, anticorps Actr, anticorps Aib1, anticorps Rac3, anticorps Src3, anticorps Tram-1, anticorps Tram1, anticorps p/Cip, anticorps pCip, anticorps actr, anticorps aib-1, anticorps aib1, anticorps cagh16, anticorps ctg26, anticorps kat13b, anticorps pcip, anticorps rac3, anticorps src-3, anticorps src3, anticorps tnrc14, anticorps tnrc16, anticorps tram-1, anticorps xSRC-3, anticorps nuclear receptor coactivator 3, anticorps nuclear receptor coactivator 3 S homeolog, anticorps NCOA3, anticorps Ncoa3, anticorps ncoa3.S

Sujet:

Synonyms: ACTR, AIB 1, AIB-1, AIB1, Amplied in breast cancer 1, Amplied in breast cancer 1 protein, bHLHe42, CAGH 16, CAGH16, CBP interacting protein, CBP-interacting protein, Class E basic helix-loop-helix protein 42, CTG 26, CTG26, KAT13B / AIB1, MGC141848, NCOA 3, NCOA 3, NCoA-3, Ncoa3, NCOA3_HUMAN, Nuclear receptor coactivator 3, pCIP, RAC 3, RAC-3, RAC3, Receptor associated coactivator 3, Receptor-associated coactivator 3, SRC 3, SRC-3, SRC3, Steroid receptor coactivator protein 3, Thyroid hormone receptor activator molecule 1, TNRC14, TNRC16, TRAM 1, TRAM-1, TRAM1.

Background: KAT13B/AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits KAT3A / KAT3B as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

ID gène: 8202

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha