PKC zeta anticorps (pThr410) (AbBy Fluor® 555)

N° du produit ABIN878196

Cet anticorps anti-PKC zeta est un anticorps Lapin Polyclonal détectant PKC zeta dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour PKC zeta anticorps (pThr410) (AbBy Fluor® 555) (ABIN878196)

Antigène: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC zeta est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PKC zeta anticorps (AbBy Fluor® 555)

Épitope: pThr410

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human PRKCZ around the phosphorylation site of Thr410

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PKC zeta

Antigène: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Autre désignation: PRKCZ

Sujet:

Synonyms: PRKCZphospho T410, PRKCZphospho Thr410, p-PRKCZT410, rotein Kinase C, AAG6, Aging associated gene 6, MGC129900, MGC129901, MGC41878, MGC57564, PKC B, PKC beta, PKC zeta, PKC2, PKCB, PKCC, PKCD, PKCE, PKCG, PRKACA, PRKC A, PRKC G, PRKCA, PRKCB, PRKCB1, PRKCB2, PRKCD, PRKCE, PRKCG, PRKCZ , Protein kinase C alpha, Protein kinase C alpha type, Protein Kinase C, Protein kinase C beta 1, Protein kinase C beta 1 polypeptide, Protein kinase C beta, Protein kinase C beta type, Protein kinase C delta, Protein kinase C epsilon, Protein kinase C gamma, Protein kinase C gamma type, Protein kinase C zeta, SCA14, Spinocerebellar ataxia 14.

Background: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

ID gène: 5590

Pathways: Signalisation NF-kappaB, Signalisation RTK, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling