KIR3DL1 anticorps (AA 250-300) (Alexa Fluor 488)

N° du produit ABIN888792

Détail du produit anti-KIR3DL1 anticorps (Alexa Fluor 488)

Antigène: KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))

Épitope: AA 250-300

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIR3DL1 est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB)

Réactivité croisée: Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse CD158e

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KIR3DL1

Antigène: KIR3DL1 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 (KIR3DL1))

Autre désignation: CD158e (KIR3DL1 Produits)

Synonymes: anticorps KIR3DL1, anticorps KIR3DL3, anticorps CD158E1, anticorps KIR, anticorps KIR3DL1/S1, anticorps NKAT3, anticorps NKB1, anticorps NKB1B, anticorps Kirl1, anticorps Kirl2, anticorps Krl1, anticorps killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1, anticorps uncharacterized LOC100437736, anticorps killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1, anticorps KIR3DL1, anticorps LOC100437736, anticorps Kir3dl1

Sujet:

Synonyms: KIR3DL1, Killer cell immunoglobulin-like receptor 3DL1, AMB11, CD158 antigen-like family member E, CD158E, CD158e antigen, CD158E1, CD158E1/2, CD158E2, CL11, CL2, HLA-BW4-specic inhibitory NK cell receptor, killer cell immunoglobulin like receptor, Killer cell immunoglobulin like receptor three domains , short cytoplasmic tail, 1, Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1, KIR, KIR antigen 3DL1, KIR G1, KIR3DS1, Kirl1, Kirl2, Krl1, MGC119726, MGC119728, MGC126589, MGC126591, MHC class I NK cell receptor, Natural killer associated transcript 3, Natural killer cell inhibitory receptor, NK receptor, NK-associated transcript 10, NK-associated transcript 3, NK-associated transcript 3delIg1, NKAT10, NKAT3, NKB1, NKB1B, p70 killer cell inhibitory receptor, p70 natural killer cell receptor clones CL 2/CL 11, KI3L1_MOUSE.

Background: KIR3DL1 (NKB1, CD158e1) is expressed on a subset of natural killer cells and T cells. NKB1 is a 70 kD member of the immunoglobulin superfamily that is expressed at varying levels among individuals. NKB1 is a type I membrane protein containing two immunoglobulin C2 type domains. The interaction of NKB1 with specific HLA B antigens on a target cell (the HLA Bw4 allele, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.

UniProt: P83555