DICER1 anticorps (AA 1301-1400) (Alexa Fluor 350)

N° du produit ABIN893989

Détail du produit anti-DICER1 anticorps (Alexa Fluor 350)

Antigène: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Épitope: AA 1301-1400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DICER1 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DICER1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DICER1

Antigène: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Autre désignation: DICER1 (DICER1 Produits)

Synonymes: anticorps dcr1, anticorps dicer, anticorps herna, anticorps DICER1, anticorps dicer1, anticorps 1110006F08Rik, anticorps D12Ertd7e, anticorps mKIAA0928, anticorps DCR1, anticorps Dicer, anticorps HERNA, anticorps MNG1, anticorps DICER, anticorps fc39d11, anticorps fc74b05, anticorps wu:fc39d11, anticorps wu:fc74b05, anticorps dicer 1, ribonuclease III, anticorps endoribonuclease Dicer, anticorps dicer 1, ribonuclease III S homeolog, anticorps dicer 1, ribonuclease type III, anticorps dicer 1 ribonuclease III, anticorps DICER1, anticorps CpipJ_CPIJ010534, anticorps dicer1, anticorps dicer1.S, anticorps Dicer1

Sujet:

Synonyms: DCR1, MNG1, Dicer, HERNA, RMSE2, Dicer1e, K12H4.8-LIKE, Endoribonuclease Dicer, Helicase with RNase motif, Helicase MOI, DICER1, KIAA0928

Background: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

ID gène: 23405

UniProt: Q9UPY3

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization