HES1 anticorps (AA 41-150) (Alexa Fluor 647)
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- Antigène Voir toutes HES1 Anticorps
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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Épitope
- AA 41-150
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HES1 est conjugé à/à la Alexa Fluor 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human HES1
- Isotype
- IgG
- Top Product
- Discover our top product HES1 Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- Autre désignation
- HES1 (HES1 Produits)
- Synonymes
- anticorps HES-1, anticorps HHL, anticorps HRY, anticorps bHLHb39, anticorps Hry, anticorps HAIRY1, anticorps c-hairy1A, anticorps Xhairy1, anticorps hairy1, anticorps hes1, anticorps Xhairy-1, anticorps Xlh1, anticorps hes family bHLH transcription factor 1, anticorps hairy and enhancer of split 1 (Drosophila), anticorps hes family bHLH transcription factor 4, anticorps hes family bHLH transcription factor 1 S homeolog, anticorps hes family bHLH transcription factor 1 L homeolog, anticorps HES1, anticorps Hes1, anticorps HES4, anticorps hes1.S, anticorps hes1.L
- Sujet
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Synonyms: HHL, HRY, HES-1, bHLHb39, Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, HES1, HL
Background: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
- ID gène
- 3280
- UniProt
- Q14469
- Pathways
- Réparation de l'ADN
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